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Nemifitide diTFA
CAS No. 204992-09-6
Nemifitide diTFA ( INN 00835 diTFA )
产品货号. M29826 CAS No. 204992-09-6
Nemifitide (diTFA) is is a synthetic pentapeptide antidepressant with a potential for rapid onset of action. Nemifitide (diTFA) is a peptide analog of melanocyte-inhibiting factor (MIF).
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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| 200MG | 获取报价 | 有现货 |
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| 500MG | 获取报价 | 有现货 |
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| 100MG | 获取报价 | 有现货 |
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| 200MG | 获取报价 | 有现货 |
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| 500MG | 获取报价 | 有现货 |
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生物学信息
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产品名称Nemifitide diTFA
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Nemifitide (diTFA) is is a synthetic pentapeptide antidepressant with a potential for rapid onset of action. Nemifitide (diTFA) is a peptide analog of melanocyte-inhibiting factor (MIF).
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产品描述Nemifitide (diTFA) is is a synthetic pentapeptide antidepressant with a potential for rapid onset of action. Nemifitide (diTFA) is a peptide analog of melanocyte-inhibiting factor (MIF). (In Vitro):In-vitro studies indicate that both nemifitide and its active metabolite (M1) bind at micromolar concentrations to several receptors including the 5-HT2A, 5-HT2C, melanocortin MC4, MC5 and bombesin.(In Vivo):Nemifitide (0.3 mg/kg; IP; daily; for 14 days) significantly increases swimming in the FSL rats after just 5 days of treatment and has long-lasting effect. Nemifitide (0.0125-15.0 mg/kg) significantly increases swimming in the FSL rats at both low (0.025-0.3 mg/kg) and high (3.0-15.0 mg/kg) doses but not at intermediate (0.4-2.4 mg/kg) doses.
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同义词INN 00835 diTFA
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通路Others
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靶点Other Targets
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受体——
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研究领域——
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适应症——
化学信息
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CAS Number204992-09-6
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分子量922.8
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分子式C37H45F7N10O10
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纯度>98% (HPLC)
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溶解度——
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SMILES——
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化学全称Sequence:{Fluoro-Phe}-{Hyp}-Arg-Gly-Trp-NH2
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
Kelly JP, et al. The effect of treatment with a new antidepressant, INN 00835, on platelet serotonin uptake in depressed patients. J Affect Disord. 1999 Oct;55(2-3):231-5.
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